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Catalog #
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AB0004
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Category
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Antibodies
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Family
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Organelle Markers
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Source
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Goat
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Application
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WB, IHC (F), IHC (P), IF
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Reactivity
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Human, Rat, Mouse, Monkey, Canine
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Description
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Goat polyclonal to ERp57 - endoplasmic reticulum lumen marker. This endoplasmic reticulum protein interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. It has disulfide isomerase activity and complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
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Alternative names
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58 kDa glucose regulated protein, 58 kDa microsomal protein, disulfide isomerase ER 60, endoplasmic reticulum resident protein 57, endoplasmic reticulum resident protein 60, ER protein 57, ER protein 60, ER protein 61, ERP57, ERp60, ERp61, glucose regulated protein 58 Kd, GRP57, GRP58, HsT17083, P58, PDIA3, phospholipase C alpha, PI PLC, protein disulfide isomerase A3 antibody.
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Gene Identifier/Accession#
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Gene ID: 2923, ENSG00000167004
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Form
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Polyclonal antibody supplied as a 200 or 500 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
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Concentration
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3.00 mg/ml
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Isotype
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IgG
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Clonality
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Polyclonal
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Conjugation
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Unconjugated
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Immunogen
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Recombinant peptide derived from within residues 300 aa to the C-terminus of human ERp57 produced in E. coli.
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Antigen Sequence
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STAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRESDFISYLQREATNPPVIQEEKPKKKKKAQEDL
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Specificity
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Detects a band of 60 kDa by Western blot in the following canine, human, monkey, mouse, rat whole cell lysates.
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Storage
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Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
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Special instructions
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Avoid freeze/thaw cycles.