Anti-REP1

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Catalog #: AB0123
Category: Antibodies
Family: Vesicle Trafficking
Source: Goat
Application: WB
Reactivity: Human, Rat, Mouse, Monkey, Canine
Description: REP1 is the component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Mutations in this protein are a cause of a type of retinal degeneration, called choroideremia.
Alternative names: CHM, choroideremia protein, DXS540, GGTA, HSD-32, RP1-93L7.1, rab escort protein 1, Rab geranylgeranyltransferase component A, REP-1, TCD antibody.
Gene Identifier/Accession#: ENSG00000188419, Gene ID: 1121
Form: Polyclonal antibody supplied as a 200 or 500 µl (4 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Concentration: 4.00 mg/ml
Isotype: IgG
Clonality: Polyclonal
Conjugation: Unconjugated
Immunogen: Purified recombinant peptide derived from within residues 617 aa - stop at the C-terminus of human Rep1 produced in E. coli.
Antigen Sequence: IIFDGDSLQPEASESSAIPEANSETFKESTNLGNLEESSE
Specificity: Detects endogenous Rep1 and in transfected cells by Western blot.
Storage: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
Special instructions: The antibody solution should be gently mixed before use.