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Catalog #
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AB0285
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Category
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Antibodies
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Family
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Neurobiology
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Source
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Goat
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Application
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WB
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Reactivity
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Human, Rat, Mouse, Monkey, Canine
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Description
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Goat polyclonal antibody to SNCB. Beta-Synuclein is a member of Synuclein family which includes alpha and gamma. SNCB inhibits phospholipase D2 and may function in neuronal plasticity. It is a non-amyloid component of senile plaques found in Alzheimer disease and can act as a regulator of SNCA aggregation process.
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Alternative names
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Beta-Synuclein, Synuclein Beta antibody.
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Gene Identifier/Accession#
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Gene ID: 6620
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Form
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Polyclonal antibody supplied as a 100 µl (2 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
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Concentration
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2.00 mg/ml
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Isotype
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IgG
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Clonality
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Polyclonal
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Conjugation
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Unconjugated
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Immunogen
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Recombinant peptide derived from within residues 80 aa to the C-terminus of human SNCB produced in E. coli.
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Antigen Sequence
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SRETGLVKREEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYEDPPQEEYQEYEPEA
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Specificity
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Detects endogenous levels of SNCB by Western blot. This Ab is specific for SNCB and does not recognizes SNCA and SNCG proteins.
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Storage
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Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
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Special instructions
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Avoid freeze/thaw cycles.
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Application
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Values
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WB
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1:500-1:5,000
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Sample
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WB
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IHC (F)
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IHC (P)
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IF
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ELISA
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Human
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+++
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ND
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ND
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ND
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ND
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Rat
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+++
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ND
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ND
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ND
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ND
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Mouse
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+++
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ND
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ND
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ND
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ND
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Canine
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+++
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ND
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ND
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ND
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ND
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Monkey
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+++
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ND
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ND
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ND
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ND
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-
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Anti-SNCB Ab at 1/1,000 dilution; mouse brain lysate at 50 µg per lane; chicken polyclonal to goat IgG (HRP) at 1/10,000 dilution.
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