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Catalog #
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AB0437
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Category
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Antibodies
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Family
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Cell Signalling
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Source
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Goat
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Application
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WB
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Reactivity
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Human, Rat, Mouse, Monkey, Canine
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Description
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Goat polyclonal antibody to MAP17. MAP17, also known as PDZK1-interacting protein 1 (PDZK1IP1), is a small membrane-associated protein of approximately 17 kDa that is highly expressed in epithelial tissues, particularly in the kidney proximal tubules. MAP17 contains a single transmembrane domain and a C-terminal PDZ-binding motif, allowing interaction with PDZ domain-containing scaffold proteins such as PDZK1. The protein has been implicated in membrane transport regulation, sodium-dependent transport processes, and cellular reactive oxygen species (ROS) signaling.
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Alternative names
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DD96, PDZK1IP, PDZK1 interacting protein 1, SPAP antibody.
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Gene Identifier/Accession#
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Gene ID: 10158, ENSG00000162366
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Form
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Polyclonal antibody supplied as a 100 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
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Concentration
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3.00 mg/ml
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Isotype
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IgG
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Clonality
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Polyclonal
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Conjugation
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Unconjugated
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Immunogen
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Purified recombinant peptide derived from within residues 47 aa to the C-terminus of human MAP17 produced in E. coli.
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Antigen Sequence
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AFAVNHFWCQEEPEPAHMILTVGNKADGVLVGTDGRYSSMAASFRSSEHENAYENVPEEEGKVRSTPM
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Specificity
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Detects MAP17 protein by Western blot.
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Storage
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Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
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Special instructions
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Avoid freeze/thaw cycles.
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Application
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Values
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WB
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1:500-1:2,500
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Sample
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WB
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IHC (F)
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IHC (P)
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IF
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ELISA
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IEM
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Human
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+++
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ND
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ND
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ND
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ND
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ND
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Rat
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+++
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ND
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ND
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ND
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ND
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ND
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Mouse
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+++
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ND
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ND
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ND
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ND
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ND
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Canine
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+++
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ND
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ND
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ND
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ND
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ND
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Monkey
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+++
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ND
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ND
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ND
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ND
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ND
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-
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MAP17 protein detected with AB0437 at 1:2,000 dilution; lysates at 50 µg per lane and rabbit polyclonal to goat IgG (HRP) at 1/10,000 dilution;
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