Anti-EWSR1
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Catalog #
AB0451
Category
Antibodies
Family
Epigenetics and Nuclear Signaling
Source
Goat
Application
None
Reactivity
Human, Rat, Mouse, Monkey, Canine
Description
Goat polyclonal antibody to EWSR1. EWSR1, or Ewing Sarcoma Breakpoint Region 1, encodes the EWS protein, a member of the FET (FUS, EWS, TAF15) family of RNA-binding proteins. These proteins are involved in various cellular processes, including gene transcription and RNA splicing. The EWS protein has a transcriptional activation domain that initiates gene transcription and an RNA-binding domain that attaches to RNA molecules. This dual functionality suggests a role in both transcription regulation and RNA processing.
Alternative names
EWS, EWS-FLI1, bK984G1.4 antibody.
Gene Identifier/Accession#
Gene ID: 2130, ENSG00000182944
Form
Polyclonal antibody supplied as a 100 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Concentration
3.00 mg/ml
Isotype
IgG
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
Purified recombinant peptide derived from within residues 140 aa to the N-terminus of human EWSR1 produced in E. coli.
Antigen Sequence
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAAT
Specificity
Detects endogenous levels of EWSR1 by Western blot in the whole cell lysates (HeLa, LS174T, H69, Jurkat, SHSY5Y, 3T3NIH, AtT20, etc.).
Storage
Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
Special instructions
Avoid freeze/thaw cycles.

Reactivity Chart

Sample WB IHC (F) IHC (P) IF ELISA IEM
Human +++ ND ND ND ND ND
Rat +++ ND ND ND ND ND
Mouse +++ ND ND ND ND ND
Monkey +++ ND ND ND ND ND
Canine +++ ND ND ND ND ND

Images

Endogenous EWSR1 detected with at 1:500 dilution; lysate at 50 µg per lane and rabbit polyclonal to goat IgG (HRP) at 1/10,000 dilution;

375 €

Quantity / Unit Size

300 µg
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