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Catalog #
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AB2295
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Category
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Antibodies
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Family
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Neurobiology
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Source
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Goat
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Application
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WB
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Reactivity
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Human, Rat, Mouse, Monkey, Canine
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Description
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Goat polyclonal antibody to SNC proteins. Members of the synuclein family of proteins (SNCA, SNCB and SNCG) are believed to be involved in the pathogenesis of neurodegenerative diseases. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease.
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Alternative names
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BCSG1, alfa-synuclein, beta-synuclein, gamma-synuclein, PD1, NACP, PARK1, PARK4, SNCA, SNCB, SNCG, SR, synuclein alpha, synuclein gamma antibody.
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Gene Identifier/Accession#
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ENSG00000145335
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Form
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Polyclonal antibody supplied as a 100 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
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Concentration
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3.00 mg/ml
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Isotype
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IgG
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Clonality
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Polyclonal
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Conjugation
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Unconjugated
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Immunogen
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Recombinant peptide derived from within residues 90 aa to the C-terminus of human SNCA, SNCB and SNCG produced in E. coli.
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Antigen Sequence
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N/A
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Specificity
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Detects endogenous levels of Synuclein proteins in brain by Western blot. This antibody recognizes SNCA, SNCB and SNCG.
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Storage
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For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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Special instructions
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The antibody solution should be gently mixed before use.
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Application
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Values
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WB
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1:500-1:2,000
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Sample
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WB
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IHC (F)
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IHC (P)
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IF
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ELISA
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Human
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+++
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ND
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ND
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ND
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ND
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Rat
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+++
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ND
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ND
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ND
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ND
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Mouse
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+++
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ND
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ND
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ND
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ND
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Monkey
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+++
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ND
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ND
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ND
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ND
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Canine
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+++
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ND
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ND
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ND
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ND
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Anti-SNC Ab at 1/1,000 dilution; lysates at 50 µg per lane; rabbit polyclonal to goat IgG (HRP) at 1/10,000 dilution;
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