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Catalog #
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AB0016
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Category
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Antibodies
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Family
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Organelle Markers
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Source
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Goat
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Application
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WB, IHC (F), IHC (P), IF
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Reactivity
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Human, Rat, Mouse, Monkey, Canine
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Description
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Goat polyclonal to connexin 43, which is a member of the connexin family. Cx43 is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. This protein is the major protein of gap junctions in embryonic development and in the heart that are thought to have a crucial role in the synchronized contraction of the heart.
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Alternative names
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AVSD3, CX43, DFNB38, gap junction protein, alpha 1, 43kDa, GJA1, GJAL HSS, HLHS1, ODDD antibody.
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Gene Identifier/Accession#
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Gene ID: 2697, ENSG00000152661
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Form
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Polyclonal antibody supplied as a 200 or 500 µl (4 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide.
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Concentration
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4.00 mg/ml
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Isotype
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IgG
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Clonality
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Polyclonal
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Conjugation
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Unconjugated
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Immunogen
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Purified recombinant peptide derived from within residues 230 aa to the C-terminus of rat CX43 produced in E. coli.
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Antigen Sequence
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VKDRVKGRSDPYHATTGPLSPSKDCGSPKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNAKKVAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
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Specificity
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Detects endogenous levels of total connexin 43.
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Storage
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Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
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Special instructions
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The antibody solution should be gently mixed before use. Avoid freeze/thaw cycles.