Anti-MUTYH

Catalog #
AB0118
Category
Antibodies
Family
Cancer
Source
Goat
Application
WB
Reactivity
Human, Rat, Mouse, Monkey, Canine
Description
Polyclonal antibody to MUTYH. MUTYH is involved in oxidative DNA damage repair. It nicks DNA replication errors, specifically A/G mismatches.
Alternative names
MYH, CYP2C, MGC4416, Myh, Mutyha, Mutyhb, Mutyhc, Mutyhbeta, Mutyhalpha, 5730495A01Rik, MGC156598, MUTYH, MGC128714, MGC145569 antibody.
Gene Identifier/Accession#
ENSG00000132781, Gene ID: 4595
Form
Polyclonal antibody supplied as a 200 µl (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Concentration
3.00 mg/ml
Isotype
IgG
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
Purified recombinant peptide derived from within residues 476 aa to the C-terminus of human Mutyh produced in E. coli.
Antigen Sequence
MKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKKPRMGQQVLDNFFRSHISTDAHSLNSAAQ
Specificity
In 293HEK cells transfected with cds plasmid (myc-his-Mutyh) detects a band of 50 kDa by Western blot.
Storage
For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
Special instructions
The antibody solution should be gently mixed before use.

Usage

Application Values
WB 1:500-1:2,000

Reactivity Chart

Sample WB IHC (F) IHC (P) IF ELISA
Human +++ ND ND ND ND
Rat +++ ND ND ND ND
Mouse +++ ND ND ND ND
Canine +++ ND ND ND ND
Monkey +++ ND ND ND ND

Images

Anti-Mutyh Ab at 1/1,000 dilution; recombinant protein at 50 ng and 293HEK transfected lysate at 100 µg per lane; rabbit polyclonal to goat IgG (HRP) at 1/10,000 dilution;

300 €

Quantity / Unit Size

600 µg
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