Anti-CANX, DyLight®488
- Catalog #
- AB41488
- Category
- Antibodies
- Family
- Loading Controls
- Source
- Goat
- Application
- WB, IHC (F), IF
- Reactivity
- Human, Rat, Mouse, Monkey, Canine
- Description
- Goat polyclonal to CANX (Calnexin) - endoplasmic reticulum (ER) membrane marker conjugated to DyLight® 488. CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
- Alternative names
- Calnexin, CALX, CNX, FLJ26570, histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 antibody.
- Gene Identifier/Accession#
- Gene ID: 821, ENSG00000127022
- Form
- Polyclonal antibody supplied as a 100 µl (2.5 mg/ml) aliquot in PBS, 20% glycerol, 0.05% ProClin® and 0.05% sodium azide.
- Concentration
- 2.50 mg/ml
- Isotype
- IgG
- Clonality
- Polyclonal
- Conjugation
- DyLight®488
- Immunogen
- Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli.
- Antigen Sequence
- KSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
- Specificity
- Detects a band of 90 kDa by Western blot whole cell lysates.
- Storage
- Store at -20 C for long-term storage. Store at 2-8 C for up to one month.
- Special instructions
- Avoid freeze/thaw cycles.
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Application Values WB 1:500-1:5,000 IF 1:50-1:500 IHC (F) 1:200-1:1,000 -
Sample WB IHC (F) IHC (P) IF ELISA Human +++ +++ ND +++ ND Rat +++ +++ ND +++ ND Mouse +++ +++ ND +++ ND Canine +++ +++ ND +++ ND Monkey +++ +++ ND +++ ND -
Immunofluorescence – anti-CANX Ab conjugated with DyLight®488 using MCR cells; cells were fixed with methanol and anti-CANX at 1/250; 
Anti-CANX Ab conjugated to DyLight@488 at 1/2,000 dilution using cell lysates at 40 µg per lane;
Usage
Reactivity Chart
Images
350 €
Quantity / Unit Size
250 µg
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